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9393


Date: May 29, 2016 at 00:43:02
From: Shirley/PA, [DNS_Address]
Subject: Long-Dreaded Superbug Found in Human and Animal in U.S.

URL: http://phenomena.nationalgeographic.com/2016/05/26/colistin-r-9/


This isn't just a simple health issue, this is a disaster that could eventually be one horrible disaster.

You don't have to believe me, nor argue about that statement. Just wait.

"...this is potentially a sentinel event..."

A sentinel event is a Patient Safety Event that reaches a patient and results in any of the following: Death.

I thought somebody would post this but I still don't see it.

Some coverage in MSM for one day, nothing since.

The ramifications of this new reality are numbing.

Mark the date someplace, May 26, 2016, and wait. In time someone you know will die of a "simple" bacterial infection that is now totally untreatable.

In time, if you are still alive, you will know many who have died of usually treatable bacterial infections like Salmonella, E.coli, Klebsiella, and Shigella.

BTW Tuberculosis, commonly known as TB, is a bacterial infection.

Further cutting back on the use of antibiotics now will not stop the spread of this new "emergence of truly pan-drug resistant bacteria.”

Nope, the horse is out of the barn, the chicken has flown the coop. Most accurately “the die is cast” from the Latin iacta alea est.

Link complete quote:

"The antibiotic resistance factor MCR, which protects bacteria against the final remaining drugs of last resort, has been found in the United States for the first time—in a person, and separately, in a stored sample taken from a slaughtered pig.

Department of Defense researchers disclosed Thursday in a report placed online by the journal Antimicrobial Agents and Chemotherapy that a 49-year-old woman who sought medical care at a military-associated clinic in Pennsylvania last month, with what seemed to be a urinary tract infection, was carrying a strain of E. coli resistant to a wide range of drugs. That turned out to be because the organism carried 15 different genes conferring antibiotic resistance, clustered on two “mobile elements” that can move easily among bacteria. One element included the new, dreaded gene mcr-1.

The discovery “heralds the emergence of truly pan-drug resistant bacteria,” the DOD personnel, Patrick McGann of the Walter Reed Army Institute of Research and Kurt Schaecher of the Walter Reed National Military Medical Center, along with eight colleagues, write in the journal report.

Beth Bell, director of the National Center for Emerging and Zoonotic Infectious Diseases at the Centers for Disease Control and Prevention, said the CDC has begun working with the researchers and the Pennsylvania Department of Health to understand how the woman came to be carrying the highly resistant bacterium. (Later Thursday, Pennsylvania Governor Tom Wolf confirmed the case, and the CDC joint investigation, in a statement.)

The DOD researchers who described her case, who did not immediately respond to a request for comment, provided no other information on her case, except to say that she had not traveled in the previous five months, suggesting she did not pick up the bacterium outside the U.S.

“It is extremely concerning; this is potentially a sentinel event,” Bell said in a phone interview. “There is a lot that needs to be done in terms of contact tracing and field investigation, to have a sense of who else might have been exposed or might be carrying this resistant bacterium.”

Bell disclosed that the U.S. Department of Agriculture will shortly announce the first identification of MCR in the United States in an animal. It was found in a stored sample of pig intestine [see links at bottom of the article: "Apocalypse Pig"] that was collected as part of the National Antimicrobial Resistance Monitoring System, a shared project of the CDC, USDA and Food and Drug Administration that looks for resistant foodborne bacteria in people, animals, and meat.

“We have been intentionally looking for this since MCR was first announced,” she said.

The Department of Health and Human Services subsequently confirmed the pig finding in a blog post Thursday afternoon.

The existence of MCR was reported for the first time just last November, in a report by British and Chinese researchers who said they had found the gene in people, animals, and meat in several areas of China. Subsequently it has been found in people, animals, or meat in at least 20 countries across the world.

MCR is so troubling because it confers protection against colistin, the last remaining antibiotic that works against a broad family of bacteria that have already acquired resistance to all the other antibiotics used against them. Colistin has worked up to this point because it is a toxic drug from the early days of the antibiotic era, seldom prescribed because of its side effects; because it was used so infrequently, bacteria had not adapted to it.

But because it is effective, agriculture adopted it instead, using it widely and legally for prevention of diseases in food animals. By the time the medical community discovered that it needed the drug back, resistance to colistin was already moving from agriculture into the human world.

Colistin is not actually used in animals in the United States, though it has been approved for use by the FDA. That makes the arrival of colistin resistance a mystery that will have to be plumbed through genetic sequencing.

Advocates who track antibiotic resistance, especially in agriculture, reacted to the news of U.S. colistin resistance by emphasizing the gravity this finding deserves.

“This shows that we are right on the verge of getting into the territory of routine bacterial infections being untreatable,” Steven Roach, the food safety program director at the Food Animal Concerns Trust, said by phone. “It underscores the failure of both the federal government and Congress, and the industry, to get a grasp of the problem. We can’t continue to drag our feet on taking needed action.”

The Pennsylvania woman’s diagnosis occurred thanks to a system set up within the DOD after MCR was discovered. Since last fall, any E. coli that was already resistant to a family of drugs known as ESBLs (extended-spectrum beta-lactams), as hers was, has been sent up the chain to Walter Reed, to be scrutinized for colistin resistance. That kind of systematic checking for antibiotic resistance, known as active surveillance, is rare in the United States. Most civilian surveillance systems are patchy; they focus only on foodborne illnesses, or rely on physicians or labs to report diagnoses, or draw from a few state health departments with already well-funded labs.

“This shows how much we need comprehensive surveillance, so that things are not discovered by accident,” Bell said. The CDC recently received additional funding under the Obama Administration’s national strategy for antibiotic resistance that will allow it to begin to set up regional lab networks. “We’ll be able to identify things systematically, identify clusters and begin contact investigations quickly,” she said.

“The first known case of MCR-1 in a U.S. patient underscores the urgent need for better surveillance and stewardship programs to combat antibiotic resistance,” agreed Dr. David Hyun, an infectious-disease specialist who is a senior officer in a long-running antibiotic resistance project at the Pew Charitable Trusts.

If there is any good news in the announcements of MCR’s appearance in the United States, it is that it has not, as yet, combined with other resistance genes into a completely untreatable organism. Bacteria acquire resistance genes like gamblers amassing a hand of cards, but the way the “cards” arrive is not step-wise—bad resistance, and then worse resistance, and then the worst—but randomly. What that means, in this case, is that the Pennsylvania E. coli possesses ESBL resistance (bad) and colistin resistance (worst)—but it remains susceptible to other intervening categories of drugs. (The stored pig sample has a yet different resistance pattern, colistin plus what is known as ASSuT, for the drug families represented by ampicillin, streptomycin, sulfas and tetracycline.)

But the random roulette of bacterial genetic recombination makes it more likely that an untreatable combination—of, for instance, colistin resistance plus carbapenem resistance, which the CDC has previously called “nightmare bacteria”—might occur. In fact, it already has occurred in patients in China, where MCR was first identified.

“We’re one step closer to carbapenem-resistant and colistin-resistant E. coli bumping into each other in someone’s gut,” Lance Price, a molecular biologist and the director of the Antibiotic Resistance Action Center at George Washington University, said by phone. “It doesn’t matter in which direction the transfer takes place—if the carbapenem-resistant strain picks up colistin resistance, or if the colistin-resistant strain picks up carbapenem resistance. It’s double jeopardy.”

Once bacteria begin to collect resistance to multiple families of antibiotics, the speed and direction of their spread becomes hard to predict, because using any of the antibiotics to which they are resistant allows them to increase in number. (Not because the drugs affect the resistant bugs—they don’t—but because they kill susceptible organisms nearby, freeing up additional living space and food.) That makes it crucial to create surveillance systems that can identify them early.

The Department of Defense system that detected the Pennsylvania organism is a model for how surveillance ought to be carried out, Price said: “We need active surveillance for multi-drug resistant or high-priority resistant organisms, in animals and people, throughout the U.S.”

[Links on link page]
Previous coverage on Phenomena:
•Feb. 1, 2016: Last-Ditch Antibiotic Resistance: What is the Role of Food?
•Jan. 7, 2016: Last-Ditch Resistance: More Countries, More Dire Results
•Jan. 6, 2016: Last-Ditch Drug Resistance: China and Europe Respond
•Dec. 20, 2015: Last-Ditch Drug Resistance: An Early Warning And Chance to Act
•Dec. 18, 2015: Resistance to a Last-Ditch Antibiotic: Invisible Spread
•Dec. 15, 2015: More Countries Are Seeing a Last-Ditch Antibiotic Failing
•Dec. 3, 2015: Apocalypse Pig Redux: Last-Resort Resistance in Europe
•Nov. 21, 2015: Apocalypse Pig: The Last Antibiotic Begins to Fail


There is no "good news" in this report.


Responses:
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9394


Date: May 29, 2016 at 00:54:48
From: Shirley/PA, [DNS_Address]
Subject: No, this isn’t the start of the antibiotic apocalypse, just bad report

URL: http://arstechnica.com/science/2016/05/everybody-be-cool-a-nightmare-superbug-has-not-heralded-the-apocalypse-yet/


For those of you who don't believe things are truly bad, then here's a different take on the above article.

This link puts it all down to "bad reporting."

It's not that bad, really. Move along, nothing to see here.

All I'd suggest is that you read the very last sentence in this article several times. Then think about just what it is telling you.



One last comment for those of you who read the "Apocalypse Pig" links in the above article. Remember a few years back all those dead pigs found floating in some Red Chinese river? Were they part of all this?


Responses:
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9396


Date: May 30, 2016 at 12:35:21
From: grzbear/AZ, [DNS_Address]
Subject: Re: No, this isn’t the start of the antibiotic apocalypse, just bad...


antibiotics were and are unnecessary... so are vaccines.

If anyone truly wishes to understand this, you have to go back in medical/political/banking cartel history well before the introduction of antibiotics and vaccines.

Pasteur was connected politically and financially and even though his experiments were utter failures, and his *germ theory* has never been proven, and is incredibly flawed because he misunderstood natural law and processes his political and financial ties won the day.

grz-


Responses:
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9398


Date: May 31, 2016 at 15:10:49
From: Shirley/PA, [DNS_Address]
Subject: Re: No, this isn’t the start of the antibiotic apocalypse, just bad...

URL: http://www.superlife.com/pasteur-bechamp-germ-theory/


I agree with you that "antibiotics were and are unnecessary...so are vaccines."

The possible "apocalypse" is that drugs have caused the mutation of so many diseases that many will die from these new "super bugs"

I am very familiar with the history of the famous "Germ Theory."

On his death bed Pasteur, creep that he was, acknowledged that Antoine Béchamp was right. See link.

The problem now is that drugs have made/encouraged nasty, nasty mutations. These mutations, as in the article I posted, will clear out (kill) folks who might have otherwise survived the original disease.

Take Tuberculosis: at the turn of the 20th Century many called it the "White Plague" and there was a growing medical fear that it had the potential to devastate the world wide population. Then, to the rescue, came new drugs and all that money. For the people who lived that was just fine.

NTL medicine knew with that drug treatment TB would eventually mutate due to the use of those drugs.

And so now we have MDR-TB & X-TB.

Nothing stops X-TB. Nothing...and it's airborne.

So the problem was created by unethical science/medicine backed by big money.

E coli & UTIs are more and more common, now with no treatment, awful treatment that it was, many will die.

Nursing Homes and hospitals will have much smaller populations.


That's the goal anyway, isn't it?


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9403


Date: June 03, 2016 at 09:44:45
From: Nasirah, [DNS_Address]
Subject: Re: there is no evidence whatsoever that Pasteur ever “recanted”

URL: Is Bill Maher really that ignorant?


Germ theory denialism

Germ theory denialism is the belief that germs do not cause infectious disease, and that the germ theory of disease is wrong. It usually involves arguing that
Louis Pasteur's model of infectious disease was wrong, and that Antoine Béchamp's was right. One of the first movements to deny the germ theory was the Sanitary
Movement, which was nevertheless central in developing America's public health infrastructure. One well-known advocate of this form of denialism is Bill Maher, who
has claimed that Pasteur recanted germ theory on his deathbed. Shikha Dalmia, writing in The Washington Examiner, referred to Maher as a "germ theory denier" after
he made these comments on Real Time with Bill Maher on March 4, 2007. However, in response to criticism of his views, Maher said, on the October 16, 2009 episode
of his show, that he accepted microorganisms as the cause of some disease, but expressed skepticism about other topics in medicine, such as vaccination. Similarly,
the following month, Maher wrote that he "understand[s] germ theory," but that he still thought that "Western medicine ignores too much [sic] the fact that the terrain
in which bacteria can thrive is crucial and often controllable, which shouldn't even be controversial."[6] Harriet Hall published an article in Skeptic where she describes
her experience arguing with germ theory denialists.

An opposite kind of pseudoscience is the belief that germs cause all diseases, including ones like cancer, which the preponderance of evidence indicates are not
caused by microorganisms[citation needed]. That belief was promoted by Hulda Regehr Clark in her book The Cure for all Cancers.


Responses:
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9402


Date: May 31, 2016 at 18:16:05
From: grzbear/AZ, [DNS_Address]
Subject: you and I are on the same page then...


have always been a fan of Béchamp - he was right and Pasteur was and is still wrong.

that simple...

your mutation references are right on as well. The more we use antibiotics and vaccines, the more we mutate and to a point become dependent upon them even though they may end up killing us off.

point being is the social engineering/indoctrination of the industry/government dogma/propaganda/religion has made most humans, including very so called intelligent ones, deaf and dumb to common sense truth - natural laws.

grz-


Responses:
None


9395


Date: May 29, 2016 at 00:59:20
From: Shirley/PA, [DNS_Address]
Subject: Goggle: dead pigs in china (NT)

URL: https://www.google.com/#q=dead+pigs+in+china


(NT)


Responses:
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